Generación de anticuerpos mediante inoculación de ADN desnudo en un modelo animal
DOI:
https://doi.org/10.29105/qh1.1-2Keywords:
Antibody, DNA transduction, SVS F proteinAbstract
Antibody generation was possible by inoculation of DNA plamids encoding the fusogenic F protein of the paramyovirus SVS in rabbit. The presence of antibodies was tested on culture cells expressing the F protein transducted with recombinant adenoviruses.
Downloads
Metrics
References
van Drunen Little-van den Hurk, S., Braun, R. P., Karvonen, B. C., King, T., Yoo, D. and Babiuk, L. A. (1999) lmmune responses and protection by DNA vaccines encoding bovine Parainfluenza virus type 3 glycoproteins. Virology. 260:35-46.
Cardoso,A. l., Blixenkrone-Moller, M., Fayolle, J., Buckland, R. and Wild, T. F. (1996)
lmmunization with plasmid DNAencoding forthe measles virus hemagglutinin and nucleoprotein leads to humoral and cell- mediated immunity. Virology. 225:293-299.
Bot,A.,Antohi, S., Bot, S., García-Sastre.A. and Bona, C. (1997) lnduction ofhumoral and cellular immunity against influenza virus by immunization of newborn mice with a plasmid bearing a hemagglutinin gene. lnternationallmmunology. 9( 11 ): 1641-1650.
Ulmer, J. B., Donnelly, J. J., Parker, S. E., Rhodes, G. H., Felger, P. L., Dwarki, V. J.,
Gromkowski, S. H., Randall Deck, R., DeWitt, C. M., Friedman,A., Hawe, L.A., Leander, K. R., Martínez, D., Perry, H. C., Shiver, J. W., Montgomery, D. L. and Liu, M.A. (1993) Heterologus protection against Influenza by injection of DNAencoding a viral protein. Science. 259:17 45 1749.
Manickan, E., Karem, K. L. and Reuse, B. T. (1997) DNAvaccines. Amoderngimmickora boon to vaccinology? Critica/ Reviews in lmmunology. 17: 139-154.
Wolff, J.A., Malone, R. W, P., Chong, W.,Acsadi, G., Jani,A. and Felnger, P. L. (1990) Direct gene transfer into mouse muscule in vivo. Science. 24 7: 1465.
Wolff, J. A. ( 1994 ). Gene therapeutics. Methods an applications of direct gene transfer. Jon A. WolffEd. Brikhauser. pp.417.
Atanasiu, P. (1962) Production de tumeurs chez le hamster par inoculation d'acid de-oxynucléique extrait de cultures de tissues infectées par le virus de polyome. Acad. Sci., 254:4228.
Wu, S. C. and Huang, G. Y. (2002) Production of retrovirus and andenovirus vectorforgene therapy: A comparativa study using microarraier and sationary cell culture. Biotechnol. Prog. 18 (3):617-622.
Gómez-TreviñoA, Castel S, López-lglesias C, Cortadellas N, Comas-Riu J, Mercadé M. (2003). Effects of adenovirus-mediated SV5 fusogenic glyciprotein expression on tumour ce lis. The Journal of Gene Medicine. 5(6):483-492 .
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2010 Alberto Gómez Treviño, Ma. Elena Cantú Cárdenaz, Eduardo l. De la Rosa Moreno, Margarita Ortiz Martinez, Arturo S. Vázquez, Elena Mercadé Gil
This work is licensed under a Creative Commons Attribution 4.0 International License.
