Síntesis verde de nanopartículas de plata mediada por Cordia boissieri: caracterización fisicoquímica y evaluación preliminar de biocompatibilidad
DOI:
https://doi.org/10.29105/qh15.02-532Keywords:
Síntesis ecológica, Nanopartículas de plata, Cordia boissieriAbstract
En este estudio, se describe una síntesis ecológica de nanopartículas de plata (AgNps) empleando los extractos metanólicos obtenidos de Cordia boissieri, que actúan como agentes estabilizadores y reductores naturales. Se prepararon dos formulaciones (AgNps-Cb244 y AgNps-Cb525) para evaluar su efecto en las propiedades físico-químicas y biocompatibilidad celular. La formación de nanopartículas se confirmó mediante espectro UV-Vis, donde se observaron bandas características del plasmón de resonancia superficial a aproximadamente 411 y 408 nm, respectivamente, las cuales se mantuvieron estables durante 21 días. El análisis de dispersión dinámica de luz (DLS) reveló tamaños de partícula promedio de alrededor de 50 nm, con baja polidispersidad y valores negativos de potencial zeta, lo que indica una buena estabilidad coloidal. Los ensayos de viabilidad celular realizados en células endoteliales humanas (HUVEC) a las 24 horas mediante el método MTS demostraron una respuesta dependiente de la concentración, con una citotoxicidad reducida en comparación con el precursor metálico (AgNO₃). En resumen, estos datos resaltan la capacidad, del extracto de C. boissieri como una alternativa para la síntesis de nanopartículas de plata con aplicaciones prometedoras en el área biomédica.
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Copyright (c) 2026 Jennifer Citlally Leos Rivera, Sleidy Pamela González Cázares, Raúl Rangel López, Sergio Arturo Galindo Rodríguez, Enrique Manuel López Cuellar, Diana Ginette Zárate Triviño
This work is licensed under a Creative Commons Attribution 4.0 International License.
